STAT3-IN-39
STAT3-IN-39 (10K) is an orally bioavailable STAT3 inhibitor with an IC50 of 0.47 μM, effectively blocking STAT3 phosphorylation. It suppresses TGF-β1-induced fibrotic responses and epithelial-mesenchymal transition in cellular models, making it a valuable research tool for studying idiopathic pulmonary fibrosis and related fibrotic diseases.
Product Specifications
CAS Number
3037596-35-0
Field of Research
Cancer Biology, Signal Transduction, Stem Cell & Developmental Biology
Smiles
O=C (C1=CC=2C=CC=CC2S1 (=O) =O) N3CCN (CC4=CC (F) =C (F) C=C4F) CC3
Molecular Formula
C20H17F3N2O3S
Molecular Weight
422.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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