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STAT3-IN-39

STAT3-IN-39 (10K) is an orally bioavailable STAT3 inhibitor with an IC50 of 0.47 μM, effectively blocking STAT3 phosphorylation. It suppresses TGF-β1-induced fibrotic responses and epithelial-mesenchymal transition in cellular models, making it a valuable research tool for studying idiopathic pulmonary fibrosis and related fibrotic diseases.

Product Specifications

CAS Number

3037596-35-0

Field of Research

Cancer Biology, Signal Transduction, Stem Cell & Developmental Biology

Smiles

O=C (C1=CC=2C=CC=CC2S1 (=O) =O) N3CCN (CC4=CC (F) =C (F) C=C4F) CC3

Molecular Formula

C20H17F3N2O3S

Molecular Weight

422.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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