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OICR41114

OICR41114 (PROTAC4) is a potent, proteasome-dependent WDR5 degrader with an EC50 of 40 nM. This bifunctional molecule, composed of a WDR5 ligand linked to an E3 ligase recruiter, is a valuable chemical probe for studying WDR5 biology and targeted protein degradation in cancer research and cellular models.

Product Specifications

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Molecular Formula

C70H83Cl2F6N9O15

Molecular Weight

1475.36

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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