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EZH2-IN-22

EZH2-IN-22 is a highly potent small molecule inhibitor of EZH2, demonstrating sub-nanomolar IC50 values against both wild-type and mutant (Y641N, Y641F) forms. Its robust antiproliferative activity supports its use in vitro for epigenetic cancer research and in vivo for studying oncogenic mechanisms in preclinical models.

Product Specifications

CAS Number

2766231-05-2

Field of Research

Epigenetics & Chromatin

Smiles

C (=C\C (O) =O) \C (O) =O.N (CC) (C1=C (C) C (C (NCC2=C (C) C=C (C) NC2=O) =O) =CC (O[C@@H]3C[C@H] (C3) N4CCCCC4) =C1) C5CCOCC5

Molecular Formula

C36H50N4O8

Molecular Weight

666.8

Storage Conditions

-20°C

Notes

For research use only.

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