MC3343
MC3343 is a dual DNMT inhibitor (IC50: 5.7 μM for DNMT1, 1.7 μM for DNMT3a) that arrests osteosarcoma cell cycle progression and induces osteogenic differentiation. It demonstrates synergistic anti-proliferative effects with adriamycin and cisplatin in vitro, supporting its research use in cancer epigenetics and combination therapy studies.
Product Specifications
CAS Number
1535187-91-7
Product Name Alternative
MC 3343
Field of Research
Epigenetics & Chromatin
Purity
99.73% (May vary between batches)
Smiles
O=C (NC=1C=CC=C (C1) NC2=NC (=NC (=C2) C) N) C=3C=CC=C (C3) NC=4C=CN=C5C=CC=CC54
Molecular Formula
C27H23N7O
Molecular Weight
461.52
Storage Conditions
-20°C
Notes
For research use only.
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