UP12
UP12 is a small molecule activator of valosin-containing protein (VCP/p97), enhancing its ATPase activity with an EC50 of 2.57 μM. This compound is a valuable research tool for investigating VCP's role in cellular processes such as protein degradation and endoplasmic reticulum-associated degradation (ERAD) in both in vitro and cell-based studies.
Product Specifications
CAS Number
443353-87-5
Field of Research
Protein Biochemistry
Smiles
O=C (NN1C (=NC=2C=CC=CC2C1=O) SCC (=O) C3=CC=C (Cl) C=C3) C=4C=CC=CC4
Molecular Formula
C23H16ClN3O3S
Molecular Weight
449.91
Storage Conditions
-20°C
Notes
For research use only.
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