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KOR agonist 3

KOR agonist 3 (Compound 5) is a potent and selective κ opioid receptor (κOR) agonist (EC50 = 0.88 nM) with significant selectivity over μOR (EC50 = 720 nM) and no δOR activity below 1 μM. It demonstrates biased signaling with minimal β-arrestin-2 recruitment compared to U50488, making it a valuable research tool for studying κOR-mediated neuropharmacology in vitro and in vivo.

Product Specifications

Field of Research

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Molecular Formula

C24H24N2O3

Molecular Weight

388.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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