NLRP3-IN-62
NLRP3-IN-62 is a potent and selective NLRP3 inflammasome inhibitor. It blocks pyroptosis in THP-1 cells (IC50 = 0.7 nM) and inhibits IL-1β release (IC50 = 108.5 nM), making it a valuable tool for studying NLRP3-driven pathologies like inflammatory and autoimmune diseases in cellular models.
Product Specifications
CAS Number
3059965-71-5
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
O=C1C=C2C (=CN1) CN (C3=NC4=NC (=CC=C4O3) C5=C (O) C=C (C=C5C) C (F) (F) F) C2
Molecular Formula
C21H15F3N4O3
Molecular Weight
428.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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