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Microtubule inhibitor 12

Microtubule inhibitor 12 (Compound 2k) is a potent anti-proliferative agent that disrupts microtubule dynamics (IC50 = 22.23 μM), leading to G2/M phase arrest, apoptosis, and inhibited migration in cancer cells. It shows low micromolar IC50 values against multiple cancer cell lines (B16-F10, A549, HepG2, MCF-7) and exhibits in vivo antitumor activity in mouse models.

Product Specifications

Field of Research

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Molecular Formula

C22H22N4O3

Molecular Weight

390.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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