WEE1 degrader 1
Compound 10 is a potent small molecule Wee1 degrader with a DC50 of 1.5 nM. It demonstrates antiproliferative activity in cancer cell assays and is a valuable chemical probe for oncology research, supporting investigations into cell cycle regulation and targeted protein degradation in both in vitro and in vivo models.
Product Specifications
Field of Research
Cancer Biology, Cell Biology
Smiles
O=C1N (C2CCC (NC2=O) =O) CC3=C1C=CC (C4=C (N (C=CC=C5) C5=N4) NC67CC8CC (CC (C7) C8) C6) =C3
Molecular Formula
C30H31N5O3
Molecular Weight
509.6
Storage Conditions
-20°C
Notes
For research use only.
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