PROTAC BRM/BRG1 degrader-4
PROTAC BRM/BRG1 degrader-4 (example 047) is a highly potent, dual-targeting degrader of the SWI/SNF ATPase subunits BRM and BRG1, with DC50 values of 0.21 nM and 3.4 nM, respectively, in SW1573 cells. This compound serves as a valuable chemical probe for investigating SWI/SNF complex function in oncology and epigenetic research, both in vitro and in vivo.
Product Specifications
Field of Research
Epigenetics & Chromatin, Neuroscience; Epigenetics & Chromatin, Pharmacology & Drug Discovery
Molecular Formula
C44H52N10O6S
Molecular Weight
849.01
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC881764-100 1x 100 µL
MMP9 (Matrix Metalloproteinase 9) (2C3), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 