PROTAC BRM/BRG1 degrader-4
PROTAC BRM/BRG1 degrader-4 (example 047) is a highly potent, dual-targeting degrader of the SWI/SNF ATPase subunits BRM and BRG1, with DC50 values of 0.21 nM and 3.4 nM, respectively, in SW1573 cells. This compound serves as a valuable chemical probe for investigating SWI/SNF complex function in oncology and epigenetic research, both in vitro and in vivo.
Product Specifications
Field of Research
Epigenetics & Chromatin, Neuroscience; Epigenetics & Chromatin, Pharmacology & Drug Discovery
Molecular Formula
C44H52N10O6S
Molecular Weight
849.01
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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