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SARS-CoV-2 Mpro-IN-31

SARS-CoV-2 Mpro-IN-31 (Compound 18) is a potent, low-nanomolar inhibitor of the SARS-CoV-2 main protease (Mpro, IC50=11 nM) and the host cysteine proteases cathepsin B (24 nM) and cathepsin L (1.8 nM) . This dual activity makes it a valuable chemical probe for studying viral replication and host cell entry mechanisms in both in vitro and cellular assays.

Product Specifications

CAS Number

870153-73-4

Field of Research

Infectious Disease & Virology

Smiles

O (C) C1=C2C (NC (C (N[C@H] (C (N[C@@H] (C[C@H]3C (=O) NCC3) C (COC (=O) C4=C (Cl) C=CC=C4Cl) =O) =O) CC (C) C) =O) =C2) =CC=C1

Molecular Formula

C31H34Cl2N4O7

Molecular Weight

645.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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