PROTAC ALK degrader-3
PROTAC ALK degrader-3 (4B) is an orally bioavailable small molecule that potently degrades ALK fusion proteins, demonstrating an IC50 of 119.33 nM in Karpas 299 cells. It effectively inhibits downstream signaling and shows antitumor potential, supporting its use in oncology research for studying ALK-driven cancers both in vitro and in vivo.
Product Specifications
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C50H60ClN9O7S
Molecular Weight
966.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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