HPK1-IN-52
HPK1-IN-52 is a potent and orally bioavailable small molecule inhibitor of hematopoietic progenitor kinase 1 (HPK1) with an IC50 of 10.4 nM. It demonstrates anti-tumor activity in research models, supporting its investigation in immuno-oncology for enhancing T cell function both in vitro and in vivo.
Product Specifications
CAS Number
2994298-66-5
Field of Research
Signal Transduction
Smiles
N (C1=C2C (=C (C=C1) C=3N4C (=NC3) C=C (F) C=C4) C=CNC2=O) C=5N=C (CN6C[C@@H] (F) CC6) C (=CC5) C7CCOCC7
Molecular Formula
C31H30F2N6O2
Molecular Weight
556.61
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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