PT109
PT109 is a multikinase inhibitor targeting JNK isoforms (IC50: 0.143-0.831 μM), SGK isoforms, and ROCK2. It exhibits anti-inflammatory and neurogenic properties and has demonstrated antiglioma activity in research by reprogramming GBM cells via the PTBP1/PKM pathway, altering their metabolic profile.
Product Specifications
CAS Number
2059104-90-2
Field of Research
Cell Biology, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Smiles
O=C (NC1CCC (NC2=CC=CC=3C=NC=CC32) CC1) CCCCC4SSCC4
Molecular Formula
C23H31N3OS2
Molecular Weight
429.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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