AZD8421
AZD8421 is a potent, selective CDK2 inhibitor (IC50 = 9 nM) that suppresses Rb phosphorylation and cell proliferation. It demonstrates significant antitumor activity in breast and ovarian cancer models, both alone and combined with CDK4/6 inhibitors, supporting its use in oncology research.
Product Specifications
CAS Number
3047321-53-6
Smiles
N (C1=C2C (N (CC) C=N2) =NC (N[C@H] ([C@@H] (C) O) CC) =N1) [C@@H]3CN (S (NCC) (=O) =O) CC3
Molecular Formula
C18H32N8O3S
Molecular Weight
440.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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