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PROTAC SMARCA2/4-degrader-25

PROTAC SMARCA2/4-degrader-25 is a heterobifunctional degrader that recruits the SMARCA2/4 bromodomain proteins to the E3 ligase VHL for ubiquitination and proteasomal degradation. This tool compound is used in vitro and in vivo to study the roles of SMARCA2/4 in cancers such as acute myeloid leukemia and synovial sarcoma.

Product Specifications

Field of Research

Epigenetics & Chromatin, Neuroscience, Pharmacology & Drug Discovery

Molecular Formula

C44H50N10O9S2

Molecular Weight

927.06

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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