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14α-Demethylase-IN-1

14α-Demethylase-IN-1 (compound 2e) is a small molecule inhibitor of the fungal enzyme 14α-demethylase, exhibiting antifungal activity against Candida species. Its in vitro MIC50 values against C. albicans, C. parapsilosis, C. krusei, and C. glabrata are 2.47 μM, 1.23 μM, 19.70 μM, and 19.70 μM, respectively, after 48 hours. This compound is a useful research tool for studying antifungal mechanisms and resistance in biochemical and microbiological assays.

Product Specifications

CAS Number

3026164-55-3

Field of Research

Infectious Disease & Virology

Smiles

FC=1C=CC (=CC1) C2=CSC (=NCCCN3CCOCC3) N2C=4C=CC=CC4

Molecular Formula

C22H24FN3OS

Molecular Weight

397.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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