14α-Demethylase-IN-1
14α-Demethylase-IN-1 (compound 2e) is a small molecule inhibitor of the fungal enzyme 14α-demethylase, exhibiting antifungal activity against Candida species. Its in vitro MIC50 values against C. albicans, C. parapsilosis, C. krusei, and C. glabrata are 2.47 μM, 1.23 μM, 19.70 μM, and 19.70 μM, respectively, after 48 hours. This compound is a useful research tool for studying antifungal mechanisms and resistance in biochemical and microbiological assays.
Product Specifications
CAS Number
3026164-55-3
Field of Research
Infectious Disease & Virology
Smiles
FC=1C=CC (=CC1) C2=CSC (=NCCCN3CCOCC3) N2C=4C=CC=CC4
Molecular Formula
C22H24FN3OS
Molecular Weight
397.51
Storage Conditions
-20°C
Notes
For research use only.
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