NsP2 Protease-IN-1

NsP2 Protease-IN-1 is a potent, irreversible covalent inhibitor of the Chikungunya virus nsP2 protease (IC50 = 60 nM) . It exhibits broad-spectrum antiviral activity against CHIKV and VEEV in vitro, with EC50 values of 0.01 μM and 0.3 μM, respectively, making it a valuable tool for studying alphavirus replication and protease function.