Isoforretin A
Isoforretin A is a potent thioredoxin-1 (Trx1) inhibitor that covalently binds to Cys32/Cys35, inducing ROS-mediated DNA damage and apoptosis in cancer cells. It has demonstrated anti-tumor efficacy in both in vitro studies and in a HepG2 xenograft mouse model, supporting its application in oncology and redox biology research.
Product Specifications
CAS Number
2231757-68-7
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction
Smiles
C[C@]12[C@]3 ([C@]4 (C[C@@] ([C@@H] (OC (C) =O) [C@@H]3OC (C) =O) (C (=C) C4=O) [H]) C[C@@H] (O) [C@@]1 (C (C) (C) [C@@H] (OC (C) =O) [C@@H] (OC (C) =O) C2) [H]) [H]
Molecular Formula
C28H38O10
Molecular Weight
534.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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