6-T-GDP
6-Thioguanosine 5'-diphosphate (6-T-GDP) is a thiopurine metabolite that acts as a Rac1 inhibitor. By suppressing Rac1 activity, it downregulates inflammatory factor transcription and adhesion molecule expression, thereby inhibiting leukocyte migration and tissue inflammation in research models. This makes it a useful tool for studying inflammatory pathways in cellular and biochemical assays.
Product Specifications
CAS Number
16541-19-8
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
O[C@H]1[C@H] (N2C3=C (N=C2) C (=S) N=C (N) N3) O[C@H] (COP (OP (=O) (O) O) (=O) O) [C@H]1O
Molecular Formula
C10H15N5O10P2S
Molecular Weight
459.27
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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