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STING antagonist 1

STINGantagonist 1 (Compound 107) is a potent and selective STING inhibitor with an IC50 of 3.8 nM in biochemical assays and 31 nM in human whole blood. This cell-permeable tool compound is valuable for investigating STING-mediated signaling in autoimmune, inflammatory, and cancer research, both in vitro and in vivo.

Product Specifications

CAS Number

3036981-21-9

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology

Smiles

CN1C (=C (N=C1C=2C (CC) =NC=3C (C2) =CN (C) N3) C=4C=5C (=NN (C[C@H] (F) C6=CC=CC=C6) C5) C=CC4) C7CC7

Molecular Formula

C31H30FN7

Molecular Weight

519.62

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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