STING antagonist 1
STINGantagonist 1 (Compound 107) is a potent and selective STING inhibitor with an IC50 of 3.8 nM in biochemical assays and 31 nM in human whole blood. This cell-permeable tool compound is valuable for investigating STING-mediated signaling in autoimmune, inflammatory, and cancer research, both in vitro and in vivo.
Product Specifications
CAS Number
3036981-21-9
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology
Smiles
CN1C (=C (N=C1C=2C (CC) =NC=3C (C2) =CN (C) N3) C=4C=5C (=NN (C[C@H] (F) C6=CC=CC=C6) C5) C=CC4) C7CC7
Molecular Formula
C31H30FN7
Molecular Weight
519.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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