TAS2940 fumarate
TAS2940 fumarate is an orally bioavailable, brain-penetrant irreversible pan-ERBB inhibitor with potent activity against wild-type HER2 (IC50 5.6 nM) and its mutants. It is a research tool for studying HER2/EGFR-driven tumors in both cellular assays and in vivo models.
Product Specifications
CAS Number
2758034-98-7
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
C (=C/C (O) =O) \C (O) =O.C (#CC1CC1) C=2N (C=3C (C2C (N[C@H] (C) C4=CC=CC=C4) =O) =C (N) N=CN3) [C@H]5CN (C (C=C) =O) [C@@H] (C) C5
Molecular Formula
C32H34N6O6
Molecular Weight
598.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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