Antitumor agent-100
Antitumor Agent-100 (A6) is an orally active molecular gel that potently induces apoptosis (IC50 = 0.3 μM) by binding PDE3A and stabilizing SLFN12 to inhibit protein translation. It demonstrates antitumor activity in cellular assays and is a chemical probe for studying PDE3A-SLFN12-dependent cell death pathways in cancer research.
Product Specifications
CAS Number
2841750-32-9
Field of Research
Cell Biology, Metabolism Research
Smiles
ClC1=C2C (NC=3N (C2) CC (=O) N3) =CC=C1C4=CC=C (C) C=C4
Molecular Formula
C17H14ClN3O
Molecular Weight
311.77
Storage Conditions
-20°C
Notes
For research use only.
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