DC-SX029
DC-SX029 is a potent small molecule inhibitor that disrupts the SNX10-PIKfyve protein-protein interaction with a K D of ~0.935 μM. It suppresses downstream TBK1/c-Rel signaling and shows research potential for inflammatory bowel disease (IBD) in cellular models, without altering SNX10 expression levels.
Product Specifications
CAS Number
300713-88-6
Field of Research
Signal Transduction
Smiles
S (NCC (CCC (O) =O) C (F) (F) F) (=O) (=O) C1=CC=C (NC (OC) =O) C=C1
Molecular Formula
C14H17F3N2O6S
Molecular Weight
398.36
Storage Conditions
-20°C
Notes
For research use only.
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254223 100 µL
PARP2 (ADP Ribosyltransferase like 2, ADPRT 2, ADPRT-2, ADPRT2, ADPRTL 2, ADPRTL 3, ADPRTL2, ADPRTL3, hPARP 2, hPARP-2, hPARP2, NAD (+) ADP Ribosyltransferase 2, NAD (+) ADP-Ribosyltransferase 2, pADPRT 2, pADPRT-2, pADPRT2, PARP 2, PARP-2, PARP2, PARP2_HUMAN, Poly (ADP ribose) Polymerase Family Member 2, Poly (ADP ribosyl) transferase like 2, poly (ADP-ribose) Polymerase 2, Poly [ADP ribose] synthetase 2, Poly [ADP-ribose]Polymerase 2, Poly (ADP ribose) synthetase, Poly[ADP-ribose] synthase 2) discontinued. See P3113-25G
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