EGFR kinase inhibitor 3
This C-linked, dual-action EGFR kinase inhibitor targets both ATP and allosteric sites, demonstrating potent sub-nanomolar activity against key mutations including L858R, T790M, and C797S. It is a valuable research tool for investigating resistance mechanisms and evaluating therapeutic strategies in both cellular and preclinical models of EGFR-driven cancers.
Product Specifications
CAS Number
2922402-03-5
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery; Cell Biology, Signal Transduction
Smiles
S (C) C=1NC (=C (N1) C=2C=C (NC (C) =O) N=CC2) C3=CC (NC (=O) C4=C5C (NC=6C (C (=O) N5) =CC=CC6) =CC=C4) =CC=C3
Molecular Formula
C31H25N7O3S
Molecular Weight
575.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC880149-500 1x 500 µL
CD106 / VCAM1 (1.4C3), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC682853-500 1x 500 µL
CD54 / ICAM-1 (15.2), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC401384-100 1x 100 µL
Ep-CAM / CD326 (Extracellular Domain) (Epithelial Marker) (EGP40/1384), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC742783-500 1x 500 µL
C1QA / Complement C1q A-Chain (C1QA/2783), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details