FGFR4-IN-17
FGFR4-IN-17 is a potent, small-molecule FGFR inhibitor with IC50 values ranging from 16.1 nM (FGFR2) to 78.0 nM (FGFR3) . This piperazinyl difluoroindan derivative demonstrates significant antitumor activity, supporting its use in cancer research for both in vitro biochemical assays and in vivo efficacy studies.
Product Specifications
CAS Number
3011805-61-8
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
FC1 (F) C=2C ([C@H] (C1) N3CCN (C) CC3) =CC=C (NC (=O) C4=CC (C#CC=5C=C (OC) C=NC5) =C (F) C=C4) C2
Molecular Formula
C29H27F3N4O2
Molecular Weight
520.55
Storage Conditions
-20°C
Notes
For research use only.
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