Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Terutroban

Terutroban (S-18886) is a selective and orally active thromboxane-prostaglandin (TP) receptor antagonist with an IC50 of 16.4 nM. Terutroban inhibits TXA2 and prostaglandin endoperoxide receptors. Terutroban is a potent antithrombotic agent and possesses anti-atherosclerotic and anti-vasoconstrictor properties[1][2][3].

Product Specifications

CAS Number

165538-40-9

Product Name Alternative

S-18886

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Terutroban.html

Purity

99.84

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(O)CCC1=C2CC[C@@H](NS(=O)(C3=CC=C(Cl)C=C3)=O)CC2=CC=C1C

Molecular Formula

C20H22ClNO4S

Molecular Weight

407.91

Precautions

H315, H319, H335

References & Citations

[1]Gelosa P, et al. Terutroban, a thromboxane/prostaglandin endoperoxide receptor antagonist, prevents hypertensive vascular hypertrophy and fibrosis. Am J Physiol Heart Circ Physiol. 2011 Mar;300 (3) :H762-8.|[2]Lesault PF, et al. Daily administration of the TP receptor antagonist terutroban improved endothelial function in high-cardiovascular-risk patients with atherosclerosis. Br J Clin Pharmacol.2011 Jun;71 (6) :844-851.|[3]Wang X, et al. Potent, long-acting cyclopentane-1,3-Dione thromboxane (A2) -receptor antagonists. ACS Med Chem Lett. 2014 Jul 24;5 (9) :1015-20.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 4

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

ROCK2 Rabbit Polyclonal Antibody
orb514496 100 µg

ROCK2 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Cmya5 siRNA Oligos set (Mouse)
16442174 3x 5 nmol

Cmya5 siRNA Oligos set (Mouse)

Sign In for Pricing
View Details
Quinolinic acid-13C3, 15N
HY-W654331-01 1 mg

Quinolinic acid-13C3, 15N

Sign In for Pricing
View Details
Quinolinic acid-13C3, 15N
HY-W654331-02 5 mg

Quinolinic acid-13C3, 15N

Sign In for Pricing
View Details
Mouse Monoclonal GPR56 Antibody (776123) [Janelia Fluor 635]
FAB4636JF635 0.1 mL

Mouse Monoclonal GPR56 Antibody (776123) [Janelia Fluor 635]

Sign In for Pricing
View Details
Fibulin-2 CRISPR Activation Plasmid (h2)
sc-403644-ACT-2 20 µg

Fibulin-2 CRISPR Activation Plasmid (h2)

Sign In for Pricing
View Details