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HSD17B13-IN-32

HSD17B13-IN-32 (Compound 67) is a potent small-molecule inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 of ≤0.1 μM against estradiol. It serves as a valuable research tool for investigating liver pathologies such as NAFLD, NASH, and drug-induced liver injury (DILI) in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

2770246-61-0

Field of Research

Metabolism Research

Smiles

N (C (=O) C1=CC (Cl) =C (O) C (Cl) =C1) C2=C3C (N=CN (CC=4C=5C (NN4) =CC=CC5) C3=O) =CC=C2

Molecular Formula

C23H15Cl2N5O3

Molecular Weight

480.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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