HSD17B13-IN-32
HSD17B13-IN-32 (Compound 67) is a potent small-molecule inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 of ≤0.1 μM against estradiol. It serves as a valuable research tool for investigating liver pathologies such as NAFLD, NASH, and drug-induced liver injury (DILI) in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2770246-61-0
Field of Research
Metabolism Research
Smiles
N (C (=O) C1=CC (Cl) =C (O) C (Cl) =C1) C2=C3C (N=CN (CC=4C=5C (NN4) =CC=CC5) C3=O) =CC=C2
Molecular Formula
C23H15Cl2N5O3
Molecular Weight
480.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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