HSD17B13-IN-42
HSD17B13-IN-42 (compound 10) is a potent small-molecule inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 below 0.1 μM. It serves as a key research tool for investigating the role of HSD17B13 in nonalcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH) in both cellular and animal models.
Product Specifications
CAS Number
2770246-10-9
Field of Research
Metabolism Research
Smiles
N (C (=O) C1=CC (Cl) =C (O) C (Cl) =C1) C2=C3C (N=CN (CC4=CC (OC (F) (F) F) =CC=C4) C3=O) =CC=C2
Molecular Formula
C23H14Cl2F3N3O4
Molecular Weight
524.28
Storage Conditions
-20°C
Notes
For research use only.
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