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MLK-IN-2

MLK-IN-2 (Compound 9a) is a potent and selective MLK3 inhibitor (IC50 = 6 nM) based on a 3H-imidazole[4,5-b]pyridine scaffold. This small molecule is a valuable research tool for studying MLK3 signaling in cancer and neurodegenerative disease models, applicable in both in vitro and in vivo experimental contexts.

Product Specifications

CAS Number

2614255-51-3

Field of Research

Signal Transduction

Smiles

N (C1=C2C (N=C (N2) C3=C (C) N (C (C) =C3) C4=CC (C (=O) N5CCOCC5) =CC=C4) =NC=C1Br) [C@@H]6CN (S (CC) (=O) =O) CC6

Molecular Formula

C29H34BrN7O4S

Molecular Weight

656.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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