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N-Hydroxysuccinimide

N-Hydroxysuccinimide (NHS) is a key reagent for activating carboxyl groups, enabling efficient conjugation with primary amines in peptide synthesis and protein cross-linking. It is widely used in vitro for preparing bioconjugates, antibody-drug conjugates (ADCs), and immobilizing biomolecules on solid supports for diagnostic and research applications.

Product Specifications

CAS Number

6066-82-6

Product Name Alternative

1-Hydroxy-2,5-pyrrolidinedione, HOSu

Purity

99.68% (May vary between batches)

Solubility

DMSO:80 mg/mL (695.11 mM) ; H2O:≥ 80 mg/mL

Smiles

O=C1N (O) C (=O) CC1

Molecular Formula

C4H5NO3

Molecular Weight

115.09

Storage Conditions

-20°C

Notes

For research use only.

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