DDC-01-163
DDC-01-163 is a potent and selective PROTAC molecule designed to degrade mutant EGFR proteins, demonstrating an IC50 of 45 nM. This compound is a valuable chemical tool for investigating mutant EGFR-driven cancers in both cellular and animal model studies.
Product Specifications
CAS Number
2140806-84-2
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C1NC (=O) C (N2C (=O) C=3C=CC=C (NCCOCCOCCOCCN4CCN (C=5N=CC (=CC5) C6=CC=C7C (=C6) C (=O) N (C7) C (C (=O) NC8=NC=CS8) C=9C=CC=CC9) CC4) C3C2=O) CC1
Molecular Formula
C49H51N9O9S
Molecular Weight
942.05
Storage Conditions
-20°C
Notes
For research use only.
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