EGFR/VEGFR2-IN-4
EGFR/VEGFR2-IN-4 (Compound 19) is a dual-targeting, irreversible inhibitor active against EGFR (IC50=18.7 nM) and VEGFR2 (IC50=102.3 nM) at 1 μM ATP. This small molecule is a valuable chemical probe for oncology research, facilitating the study of EGFR and VEGFR2 signaling pathways in both cellular and animal models of cancer.
Product Specifications
CAS Number
870962-74-6
Field of Research
Cardiovascular Research, Cardiovascular Research; Cell Biology, Signal Transduction
Smiles
N (C=1C2=C (C=C (OCC) C (NC (/C=C/CN (C) C) =O) =C2) N=CN1) C=3C (=O) C=C (OCC4=CC=CC=C4) C (=O) C3
Molecular Formula
C29H29N5O5
Molecular Weight
527.57
Storage Conditions
-20°C
Notes
For research use only.
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