NLRP3-IN-56
NLRP3-IN-56 (compound 062) is a potent, nanomolar NLRP3 inflammasome inhibitor, suppressing IL-1β release in THP-1 cells with an IC50 of 9.7 nM. It is a valuable research tool for studying NLRP3-driven pathologies, including inflammatory and autoimmune diseases, in both cellular and animal models.
Product Specifications
CAS Number
3048421-42-4
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
N (C[C@@H] (CO) O) C=1C2=C (C (=NN1) C3=C (O) C=C (Cl) C=C3) C=CC (C#CC) =C2
Molecular Formula
C20H18ClN3O3
Molecular Weight
383.83
Storage Conditions
-20°C
Notes
For research use only.
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