Aderbasib
Aderbasib (INCB007839) is a potent, orally bioavailable dual inhibitor of ADAM10 and ADAM17. It is utilized in cancer and cardiovascular research, where its activity in blocking ectodomain shedding has been investigated in both cellular assays and in vivo tumor models.
Product Specifications
CAS Number
791828-58-5
Product Name Alternative
Aderbasib, INCB007839, INCB-007839, INCB 7839, INCB7839, INCB-7839, INCB 007839
Field of Research
Immunology & Inflammation, Protein Biochemistry
Purity
97.82% (May vary between batches)
Solubility
DMSO:80 mg/mL (192.09 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.92 mM)
Smiles
C (NO) (=O) [C@H]1CC2 (CN (C (OC) =O) [C@@H]1C (=O) N3CCN (CC3) C4=CC=CC=C4) CC2
Molecular Formula
C21H28N4O5
Molecular Weight
416.47
Storage Conditions
-20°C
Notes
For research use only.
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