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TLR7 agonist 17

Compound 20 is a potent small molecule TLR7 agonist with EC50 values of 12 nM (hTLR7) and 17 nM (mTLR7) . It is utilized in immuno-oncology research to study innate immune activation and has demonstrated anticancer activity in both cellular assays and in vivo tumor models.

Product Specifications

CAS Number

2410517-32-5

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology

Smiles

C (N1C2=C (N[C@@H] (CCC) CCO) N=C (N) N=C2C=N1) C3=C (OC) C=C (CNC4CCOCC4) C=C3

Molecular Formula

C25H37N7O3

Molecular Weight

483.61

Storage Conditions

-20°C

Notes

For research use only.

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