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TRK-IN-28

TRK-IN-28 (compound 30f) is a potent TRK inhibitor with IC50 values of 0.55 nM (TRK WT), 25.1 nM (TRK G595R), and 5.4 nM (TRK G667C) . This small molecule is a valuable research tool for investigating TRK kinase biology and resistance mutations in both cellular and biochemical assays.

Product Specifications

CAS Number

2991504-43-7

Field of Research

Signal Transduction

Smiles

N (C=1C=2C (NN1) =CC=C (CC3=CC (F) =CC (F) =C3) C2) C=4C5=C (C=C (C=C5) N6CCN (C) CC6) N=CN4

Molecular Formula

C27H25F2N7

Molecular Weight

485.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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