TRK-IN-28
TRK-IN-28 (compound 30f) is a potent TRK inhibitor with IC50 values of 0.55 nM (TRK WT), 25.1 nM (TRK G595R), and 5.4 nM (TRK G667C) . This small molecule is a valuable research tool for investigating TRK kinase biology and resistance mutations in both cellular and biochemical assays.
Product Specifications
CAS Number
2991504-43-7
Field of Research
Signal Transduction
Smiles
N (C=1C=2C (NN1) =CC=C (CC3=CC (F) =CC (F) =C3) C2) C=4C5=C (C=C (C=C5) N6CCN (C) CC6) N=CN4
Molecular Formula
C27H25F2N7
Molecular Weight
485.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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