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Tyk2-IN-15

Tyk2-IN-15 (Compound 97) is a potent and selective Tyk2 inhibitor, demonstrating an IC50 of ≤10 nM against the Tyk2-JH2 pseudokinase domain. This tool compound is used in preclinical research to investigate signaling pathways in autoimmune and inflammatory disease models, both in cellular and animal studies.

Product Specifications

CAS Number

3010873-44-3

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Smiles

N (C (C) =O) C=1C=C2N (N=C (C2=CN1) N3C[C@@H] (N (C) C) CC3) C=4N=C (C (C) (F) F) C=CC4

Molecular Formula

C21H25F2N7O

Molecular Weight

429.47

Storage Conditions

-20°C

Notes

For research use only.

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