Tyk2-IN-16
Tyk2-IN-16 is a highly potent and selective TYK2 pseudokinase (JH2) domain inhibitor, demonstrating sub-10 nM IC50 values against both the isolated domain and pSTAT4 in NK92 cells. This tool compound is valuable for investigating TYK2-mediated signaling in autoimmune and inflammatory disease research, as evidenced in the patent literature.
Product Specifications
CAS Number
3010874-30-0
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
N (C (C) =O) C=1C=C2C (C (=NN2C=3N=C (C (C) (F) F) C=CN3) N4CC (C#N) (C) CC4) =CN1
Molecular Formula
C20H20F2N8O
Molecular Weight
426.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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