UCM-13369
UCM-13369 (Compound 4b) is a small molecule inhibitor that selectively targets the C-terminal domain of mutant NPM1, downregulating its oncogenic pathway and inducing apoptosis in AML models. This tool compound is used in vitro and in vivo for researching acute myeloid leukemia mechanisms and therapeutic strategies.
Product Specifications
CAS Number
2921944-77-4
Field of Research
Cell Biology
Smiles
C (CNCC1CC1) [C@@H]2C3=C (C[C@@H] ([C@H]2N) C4=CC=C (OC) C=C4) NC=5C3=CC=CC5
Molecular Formula
C25H31N3O
Molecular Weight
389.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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