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Vatalanib hydrochloride

Vatalanib hydrochloride (PTK787 hydrochloride) is a potent, orally active VEGF receptor tyrosine kinase inhibitor. It has demonstrated efficacy in reducing cortical Aβ plaque burden in 5xFAD Alzheimer's disease mouse models and is also widely used in oncology research to study angiogenesis in vitro and in vivo.

Product Specifications

CAS Number

212141-52-1

Product Name Alternative

CGP797870 hydrochloride, CGP-797870 hydrochloride, Apoptosis, ZK222584 hydrochloride, ZK-222584 hydrochloride, PTK787 hydrochloride, PTK 787 hydrochloride, VEGFR2

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Purity

99.70% (May vary between batches)

Solubility

DMSO:50 mg/mL (130.46 mM)

Smiles

Cl.ClC1=CC=C (C=C1) NC2=NN=C (C=3C=CC=CC23) CC=4C=CN=CC4

Molecular Formula

C20H16Cl2N4

Molecular Weight

383.27

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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