Vatalanib hydrochloride
Vatalanib hydrochloride (PTK787 hydrochloride) is a potent, orally active VEGF receptor tyrosine kinase inhibitor. It has demonstrated efficacy in reducing cortical Aβ plaque burden in 5xFAD Alzheimer's disease mouse models and is also widely used in oncology research to study angiogenesis in vitro and in vivo.
Product Specifications
CAS Number
212141-52-1
Product Name Alternative
CGP797870 hydrochloride, CGP-797870 hydrochloride, Apoptosis, ZK222584 hydrochloride, ZK-222584 hydrochloride, PTK787 hydrochloride, PTK 787 hydrochloride, VEGFR2
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
99.70% (May vary between batches)
Solubility
DMSO:50 mg/mL (130.46 mM)
Smiles
Cl.ClC1=CC=C (C=C1) NC2=NN=C (C=3C=CC=CC23) CC=4C=CN=CC4
Molecular Formula
C20H16Cl2N4
Molecular Weight
383.27
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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