VL285 Phenol
VL285 Phenol is a VHL-based small molecule ligand and a phenol-containing analog of VL285. It functions as a degrader in the HaloPROTAC3 system, inducing the degradation of HaloTag7 fusion proteins with an IC50 of 0.34 μM in cellular studies.
Product Specifications
CAS Number
1448188-69-9
Field of Research
Pharmacology & Drug Discovery
Smiles
[C@@H] (C (=O) N1[C@H] (C (NCC2=C (O) C=C (C=C2) C3=C (C) N=CS3) =O) C[C@@H] (O) C1) ([C@H] (C) C) N4C (=O) C=5C (C4) =CC=CC5
Molecular Formula
C29H32N4O5S
Molecular Weight
548.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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