WNTinib
WNTinib (APS-8-100-2) is a multi-kinase inhibitor designed to selectively target CTNNB1-mutated hepatocellular carcinoma. It suppresses oncogenic Wnt signaling by inhibiting KIT/MAPK pathways and subsequent EZH2 activation, showing utility in both in vitro and in vivo HCC research models.
Product Specifications
CAS Number
2770091-44-4
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Smiles
O (C=1C=C (C (NC) =O) N=CC1) C2=CC (F) =C (NC (NC3=CC=C (C (C (F) (F) F) (F) F) C=C3) =O) C=C2
Molecular Formula
C22H16F6N4O3
Molecular Weight
498.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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