WRN inhibitor 7
WRN inhibitor 7 (Compound h6) is a potent small molecule targeting Werner syndrome helicase, inhibiting its helicase and ATPase activities with IC50 values of 9.8 μM and 15.8 μM, respectively. It is a valuable research tool for studying DNA repair mechanisms and synthetic lethality in microsatellite instable (MSI) cancer models in vitro.
Product Specifications
CAS Number
444780-45-4
Field of Research
Cell Biology, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology
Smiles
C (=C1C (=O) N (CC (NC2=CC=C (C) C=C2) =O) C (=O) N1) C3=C (OCC4=CC (C (O) =O) =CC=C4) C=CC=C3
Molecular Formula
C27H23N3O6
Molecular Weight
485.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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