XRD-0394
XRD-0394 is a potent, selective, and orally bioavailable dual inhibitor of ATM and DNA-PKcs. It synergistically enhances the cytotoxic effects of ionizing radiation in tumor models and improves the activity of PARP and topoisomerase I inhibitors in cellular studies, supporting its investigation in DNA damage response and cancer therapy research.
Product Specifications
CAS Number
2595308-10-2
Field of Research
Molecular Biology, Signal Transduction
Smiles
O=C1C2 (C=3C=4C (N=CC3N1C) =CC (F) =C (C4) C=5C=C (NS (C) (=O) =O) C (OCCNC (C) C) =NC5) CCC2
Molecular Formula
C26H30FN5O4S
Molecular Weight
527.61
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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